In a collaboration with Sara Lena Weinhold and Robert Göder at the Christian-Albrechts-University Kiel, Hong-Viet V. Ngo recently published a study investigating the influence of auditory stimulation during sleep on memory consolidation in people with schizophrenia.
The study shows that auditory stimulation targeting slow oscillations – a key rhythm mediating memory processing – in real-time in people with schizophrenia results in an electrophysiological response that is similar to that in healthy participants. Albeit an absent effect of stimulation on memory consolidation, the authors found the stronger the slow oscillation enhancement the less participants forgot, i.e., the better memory performance was, the following morning.
Thus, this paper not only confirms the overall feasibility of this approach and provides essential electrophysiological insights. It furthermore highlights the potential of auditory stimulation to provide alternative treatments for sleep-related dysfunctions in patients with schizophrenia. The article is available here.