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Auditory Cortex Auditory Neuroscience Auditory Perception EEG / MEG Neural Oscillations Papers Publications Speech

New paper: Her­rmann, Hen­ry, Hae­gens & Obleser in Neuroimage

And again, AC-Alum­ni Björn Her­rmann got a new paper in press / online at Neu­roIm­age on

Tem­po­ral expec­ta­tions and neur­al ampli­tude fluc­tu­a­tions in audi­to­ry cor­tex inter­ac­tive­ly influ­ence perception

Abstract
Align­ment of neur­al oscil­la­tions with tem­po­ral­ly reg­u­lar input allows lis­ten­ers to gen­er­ate tem­po­ral expec­ta­tions. How­ev­er, it remains unclear how behav­ior is gov­erned in the con­text of tem­po­ral vari­abil­i­ty: What role do tem­po­ral expec­ta­tions play, and how do they inter­act with the strength of neur­al oscil­la­to­ry activ­i­ty? Here, human par­tic­i­pants detect­ed near-thresh­old tar­gets in tem­po­ral­ly vari­able acoustic sequences. Tem­po­ral expec­ta­tion strength was esti­mat­ed using an oscil­la­tor mod­el and pre-tar­get neur­al ampli­tudes in audi­to­ry cor­tex were extract­ed from mag­ne­toen­cephalog­ra­phy sig­nals. Tem­po­ral expec­ta­tions mod­u­lat­ed tar­get-detec­tion per­for­mance, how­ev­er, only when neur­al delta-band ampli­tudes were large. Thus, slow neur­al oscil­la­tions act to gate influ­ences of tem­po­ral expec­ta­tion on per­cep­tion. Fur­ther­more, slow ampli­tude fluc­tu­a­tions gov­erned lin­ear and qua­drat­ic influ­ences of audi­to­ry alpha-band activ­i­ty on per­for­mance. By fus­ing a mod­el of tem­po­ral expec­ta­tion with neur­al oscil­la­to­ry dynam­ics, the cur­rent find­ings show that human per­cep­tion in tem­po­ral­ly vari­able con­texts relies on com­plex inter­ac­tions between mul­ti­ple neur­al fre­quen­cy bands.

Cheers.

Ref­er­ences

  • Her­rmann B1, Hen­ry MJ2, Hae­gens S3, Obleser J4. Tem­po­ral expec­ta­tions and neur­al ampli­tude fluc­tu­a­tions in audi­to­ry cor­tex inter­ac­tive­ly influ­ence per­cep­tion. Neu­roim­age. 2015 Sep 18;124(Pt A):487–497. PMID: 26386347. [Open with Read]
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Papers Publications

Sen­si­tiv­i­ty of rat infe­ri­or col­licu­lus neu­rons to fre­quen­cy dis­tri­b­u­tions by Her­rmann et al.

New paper in press by AC Alum­ni Björn Her­rman in col­lab­o­ra­tion with Ed Bartlett and col­leagues from Pur­due Uni­ver­si­ty on stim­u­lus-sta­tis­ti­cal and stim­u­lus-spe­cif­ic adap­ta­tion in the rat infe­ri­or col­licu­lus that will appear soon in the Jour­nal of Neurophysiology.

Sen­si­tiv­i­ty of rat infe­ri­or col­licu­lus neu­rons to fre­quen­cy distributions

Abstract
Stim­u­lus-spe­cif­ic adap­ta­tion refers to a neur­al response reduc­tion to a repeat­ed stim­u­lus that does not gen­er­al­ize to oth­er stim­uli. How­ev­er, stim­u­lus-spe­cif­ic adap­ta­tion appears be influ­enced by addi­tion­al fac­tors. For exam­ple, the sta­tis­ti­cal dis­tri­b­u­tion of tone fre­quen­cies has recent­ly been shown to dynam­i­cal­ly alter stim­u­lus-spe­cif­ic adap­ta­tion in human audi­to­ry cor­tex. The cur­rent study inves­ti­gat­ed whether sta­tis­ti­cal stim­u­lus dis­tri­b­u­tions also affect stim­u­lus-spe­cif­ic adap­ta­tion at an ear­li­er stage of the audi­to­ry hier­ar­chy. Neur­al spik­ing activ­i­ty and local field poten­tials were record­ed from infe­ri­or col­licu­lus neu­rons of rats while tones were pre­sent­ed in odd­ball sequences that formed two dif­fer­ent sta­tis­ti­cal con­texts. Each sequence con­sist­ed of a repeat­ed­ly pre­sent­ed tone (stan­dard) and three rare deviants of dif­fer­ent mag­ni­tudes (small, mod­er­ate, large spec­tral change). The crit­i­cal manip­u­la­tion was the rel­a­tive prob­a­bil­i­ty with which large spec­tral changes occurred. In one con­text, the prob­a­bil­i­ty was high (rel­a­tive to all deviants) while it was low in the oth­er con­text. We observed larg­er respons­es for deviants com­pared to stan­dards, con­firm­ing pre­vi­ous reports of increased response adap­ta­tion for fre­quent­ly pre­sent­ed tones. Impor­tant­ly, the sta­tis­ti­cal con­text in which tones were pre­sent­ed strong­ly mod­u­lat­ed stim­u­lus-spe­cif­ic adap­ta­tion. Phys­i­cal­ly and prob­a­bilis­ti­cal­ly iden­ti­cal stim­uli (mod­er­ate deviants) in the two sta­tis­ti­cal con­texts elicit­ed dif­fer­ent respons­es mag­ni­tudes con­sis­tent with neur­al gain changes and thus neur­al sen­si­tiv­i­ty adjust­ments induced by the spec­tral range of a stim­u­lus dis­tri­b­u­tion. The data show that already at the lev­el of the infe­ri­or col­licu­lus stim­u­lus-spe­cif­ic adap­ta­tion is dynam­i­cal­ly altered by the sta­tis­ti­cal con­text in which stim­uli occur.

Ref­er­ences

  • Her­rmann B1, Parthasarathy A2, Han EX, Obleser J3, Bartlett EL2. Sen­si­tiv­i­ty of rat infe­ri­or col­licu­lus neu­rons to fre­quen­cy dis­tri­b­u­tions. J Neu­ro­phys­i­ol. 2015 Sep 9:jn. PMID: 26354316. [Open with Read]
Categories
Ageing Auditory Speech Processing Degraded Acoustics Hearing Loss Media Publications Speech

Quick inter­view for detektor.fm

Based on Malte’s recent J Neu­rosci study, Jonas did a brief inter­view for Ger­man radio detektor.fm today and talked lis­ten­ing effort, dig­i­tal phone lines, noise reduc­tion, and next-gen­er­a­tion hear­ing aids with host Tere­sa Nehm. (In Ger­man only.)

Categories
Auditory Speech Processing EEG / MEG Linguistics Papers Publications Speech

New edi­to­r­i­al in “Brain & Lan­guage”: Re-vis­it­ing the elec­tro­phys­i­ol­o­gy of language

I had the hon­our of guest-edit­ing a spe­cial issue for the clas­sic jour­nal “Brain and Lan­guage” and have thus con­tributed a brief edi­to­r­i­al (now online) to this issue. The spe­cial issue re-vis­its old themes and new leads in the elec­tro­phys­i­ol­o­gy of speech, lan­guage, and its precursors.

UPDATE: The full spe­cial issue appeared in Sep­tem­ber 2015 and all arti­cles are now acces­si­ble and citable. Thanks for your kind attention!

Categories
EEG / MEG Neural Oscillations Neural Phase Papers Publications

Strauß again — in Jour­nal of Neuroscience

Alum­na Dr. Antje Strauß just got anoth­er paper on:

Alpha Phase Deter­mines Suc­cess­ful Lex­i­cal Deci­sion in Noise

by Antje Strauß, Mol­ly Hen­ry, Math­ias Scharinger, and Jonas Obleser

appeared in Jour­nal of Neu­ro­science. Check the abstract below;

Abstract
Psy­chophys­i­cal tar­get detec­tion has been shown to be mod­u­lat­ed by slow oscil­la­to­ry brain phase. How­ev­er, thus far, only low-lev­el sen­so­ry stim­uli have been used as tar­gets. The cur­rent human elec­troen­cephalog­ra­phy (EEG) study exam­ined the influ­ence of neur­al oscil­la­to­ry phase on a lex­i­cal-deci­sion task per­formed for stim­uli embed­ded in noise. Neur­al phase angles were com­pared for cor­rect ver­sus incor­rect lex­i­cal deci­sions using a phase bifur­ca­tion index (BI), which quan­ti­fies dif­fer­ences in mean phase angles and phase con­cen­tra­tions between cor­rect and incor­rect tri­als. Neur­al phase angles in the alpha fre­quen­cy range (8–12 Hz) over right ante­ri­or sen­sors were approx­i­mate­ly antiphase in a pres­tim­u­lus time win­dow, and thus suc­cess­ful­ly dis­tin­guished between cor­rect and incor­rect lex­i­cal deci­sions. More­over, alpha-band oscil­la­tions were again approx­i­mate­ly antiphase across par­tic­i­pants for cor­rect ver­sus incor­rect tri­als dur­ing a lat­er peri­s­tim­u­lus time win­dow (∼500 ms) at left-cen­tral elec­trodes. Strik­ing­ly, lex­i­cal deci­sion accu­ra­cy was not pre­dict­ed by either event-relat­ed poten­tials (ERPs) or oscil­la­to­ry pow­er mea­sures. We sug­gest that cor­rect lex­i­cal deci­sions depend both on suc­cess­ful sen­so­ry pro­cess­ing, which is made pos­si­ble by the align­ment of stim­u­lus onset with an opti­mal alpha phase, as well as inte­gra­tion and weight­ing of deci­sion­al infor­ma­tion, which is cou­pled to alpha phase imme­di­ate­ly fol­low­ing the crit­i­cal manip­u­la­tion that dif­fer­en­ti­at­ed words from pseu­do­words. The cur­rent study con­sti­tutes a first step toward char­ac­ter­iz­ing the role of dynam­ic oscil­la­to­ry brain states for high­er cog­ni­tive func­tions, such as spo­ken word recognition.
Categories
EEG / MEG Neural Oscillations Neural Phase Papers Publications

New Paper out in Psy­chophys­i­ol­o­gy — Wilsch et al.

A new paper on

Slow-delta phase con­cen­tra­tion marks improved tem­po­ral expec­ta­tions based on the pas­sage of time

by AC PhD Anna Wilsch, alum­ni post­docs Mol­ly Hen­ry & Björn Her­rmann, AC head Jonas Obleser along with Burkhard Maess appeared in Psychophysiology.

Check the online source, or take a quick look on the abstract below.

Abstract
Tem­po­ral expec­ta­tions enhance neur­al encod­ing pre­ci­sion, reflect­ed in opti­mized align­ment of slow neur­al oscil­la­to­ry phase, and facil­i­tate sub­se­quent stim­u­lus pro­cess­ing. If an even­t’s exact occur­rence time is unknown, tem­po­ral expec­ta­tions arise sole­ly from the pas­sage of time. Here, we show that this spe­cif­ic type of tem­po­ral expec­ta­tion is also reflect­ed in neur­al phase orga­ni­za­tion. While under­go­ing mag­ne­toen­cephalog­ra­phy, par­tic­i­pants per­formed an audi­to­ry-delayed match­ing-to-sam­ple task with two syl­la­bles (S1, S2). Crit­i­cal­ly, S1-onset time var­ied in the 0.6–1.8‑s (i.e., 0.6−1.7 Hz) range. Increas­ing S1-onset times led to increased slow-delta (0.6−0.9 Hz) phase coher­ence over right fron­totem­po­ral sen­sors dur­ing S1 encod­ing. More­over, indi­vid­u­als with high­er slow-delta coher­ence showed decreased alpha pow­er (8−13 Hz) dur­ing sub­se­quent mem­o­ry reten­tion. In sum, tem­po­ral expec­ta­tions based on the pas­sage of time opti­mize the pre­cise align­ment of neur­al oscil­la­to­ry phase with an expect­ed stimulus.

Ref­er­ences

  • Wilsch A1, Hen­ry MJ, Her­rmann B, Maess B, Obleser J. Slow-delta phase con­cen­tra­tion marks improved tem­po­ral expec­ta­tions based on the pas­sage of time. Psy­chophys­i­ol­o­gy. 2015 Feb 16. PMID: 25684032. [Open with Read]
Categories
Auditory Cortex Auditory Neuroscience Clinical relevance Degraded Acoustics EEG / MEG Executive Functions Hearing Loss Media Neural Oscillations Papers Publications Speech

Max Planck Soci­ety reports on Wöst­mann et al.’s Neur­al alpha dynamics

Some days ago the Max Planck Soci­ety put out a news fea­ture on our most recent Jour­nal of Neu­ro­science paper (see our post):

Aufmerk­sam zuhören — Hirn-Wellen zeigen Mühen des Hörens im Alter an

Sum­ma­ry
Ältere Men­schen kla­gen oft über Hörschwierigkeit­en, beson­ders wenn mehrere Per­so­n­en durcheinan­der sprechen. Forsch­er am Max-Planck-Insti­tut für Kog­ni­tions- und Neu­rowis­senschaften in Leipzig haben her­aus­ge­fun­den, dass der Grund hier­für nicht nur im Ohr, son­dern eben­so in verän­derten Aufmerk­samkeit­sprozessen im Gehirn älter­er Men­schen zu find­en ist. Eine beson­dere Bedeu­tung kommt dabei den Alpha-Wellen zu, deren Anpas­sung an verän­derte Hör­si­t­u­a­tio­nen das Sprachver­ständ­nis in All­t­agssi­t­u­a­tio­nen verbessert.

It nice­ly wraps up Malte’s exper­i­ment on alpha dynam­ics in younger and old­er lis­ten­ers. Check the link above for the full arti­cle (Ger­man).

 

Ref­er­ences

  • Wöst­mann M1, Her­rmann B2, Wilsch A2, Obleser J3. Neur­al alpha dynam­ics in younger and old­er lis­ten­ers reflect acoustic chal­lenges and pre­dic­tive ben­e­fits. J Neu­rosci. 2015 Jan 28;35(4):1458–67. PMID: 25632123. [Open with Read]
Categories
Degraded Acoustics EEG / MEG Linguistics Neural Oscillations Neural Phase Papers Perception Publications Speech

New paper in press in the Jour­nal of Neu­ro­science: Strauß, Hen­ry, Scharinger, & Obleser

Con­grat­u­la­tions to just-grad­u­at­ed for­mer AC PhD stu­dent and fresh GIPSA/Grenoble Post­doc Antje Strauß, who today had the last data set from her PhD the­sis accept­ed as a paper in The Jour­nal of Neu­ro­science. We are all very happy!

The paper is enti­tled “Alpha phase deter­mines suc­cess­ful lex­i­cal deci­sion in noise” and con­tains arguably the first data set to extend prin­ci­ples of (alpha, 8–12 Hz) pre-stim­u­lus phase depen­dence from low-lev­el psy­chophysics to more com­plex lan­guage or cog­ni­tive process­es, here: lex­i­cal decision.

A big hel­lo to AC friend and col­league Niko Busch, by the way, whose bifur­ca­tion index mea­sure served our pur­pos­es very well here!

We will update accord­ing­ly, but mean­while, here is the abstract and my favourite fig­ure from the paper.

Abstract
Psy­chophys­i­cal tar­get detec­tion has been shown to be mod­u­lat­ed by slow oscil­la­to­ry brain phase. How­ev­er, thus far, only low-lev­el sen­so­ry stim­uli have been used as tar­gets. The cur­rent human elec­troen­cephalog­ra­phy study exam­ined the influ­ence of neur­al oscil­la­to­ry phase on a lex­i­cal-deci­sion task per­formed for stim­uli embed­ded in noise. Neur­al phase angles were com­pared for cor­rect ver­sus incor­rect lex­i­cal deci­sions using a phase bifur­ca­tion index, which quan­ti­fies dif­fer­ences in mean phase angles and phase con­cen­tra­tions between cor­rect and incor­rect tri­als. Neur­al phase angles in the alpha fre­quen­cy range (8–12 Hz) over right ante­ri­or sen­sors were approx­i­mate­ly anti-phase in a pre-stim­u­lus time win­dow, and thus suc­cess­ful­ly dis­tin­guished between cor­rect and incor­rect lex­i­cal deci­sions. More­over, alpha-band oscil­la­tions were again approx­i­mate­ly anti-phase across par­tic­i­pants for cor­rect ver­sus incor­rect tri­als dur­ing a lat­er peri-stim­u­lus time-win­dow (around 500 ms) at left-cen­tral elec­trodes. Strik­ing­ly, lex­i­cal deci­sion accu­ra­cy was not pre­dict­ed by either ERPs or oscil­la­to­ry pow­er mea­sures. We sug­gest that cor­rect lex­i­cal deci­sions depend both on suc­cess­ful sen­so­ry pro­cess­ing, which is made pos­si­ble by the align­ment of stim­u­lus onset with an opti­mal alpha phase, as well as inte­gra­tion and weight­ing of deci­sion­al infor­ma­tion, which is cou­pled to alpha phase imme­di­ate­ly fol­low­ing the crit­i­cal manip­u­la­tion that dif­fer­en­ti­at­ed words from pseu­do­words. The cur­rent study con­sti­tutes a first step towards char­ac­ter­iz­ing the role of dynam­ic oscil­la­to­ry brain states for high­er cog­ni­tive func­tions such as spo­ken word recognition.

Untitled copy