Obleserlab postdoc Mohsen Alavash and Obleserlab Alumna Sung-Joo Lim are in press at Neuroimage!
They argue with data from a placebo-controlled dopaminergic intervention study that BOLD signal variability and the functional connectome are surprisingly clearly affected by L-Dopa, and (ii) that the degree of change in these metrics can explain the degree to which individuals will profit from L-DOPA in performing the challenging listening task (while others dont; Preprint here ).
Alavash, M., Lim, S.J., Thiel, C., Sehm, B., Deserno, L., & Obleser, J. (2018) Dopaminergic modulation of hemodynamic signal variability and the functional connectome during cognitive performance. Neuroimage. In press.
— Thanks also and in particular to our colleagues Christiane Thiel of Oldenburg, and Bernhard Sehm and Lorenz Deserno of Leipzig, who helped us made this large-scale L-DOPA project happen!