Obleserlab postdoc Mohsen Alavash and Obleserlab Alumna Sung-Joo Lim are in press at Neuroimage!
They argue with data from a placebo-controlled dopaminergic intervention study that BOLD signal variability and the functional connectome are surprisingly clearly affected by L‑Dopa, and (ii) that the degree of change in these metrics can explain the degree to which individuals will profit from L‑DOPA in performing the challenging listening task (while others dont; Preprint here ).
Alavash, M., Lim, S.J., Thiel, C., Sehm, B., Deserno, L., & Obleser, J. (2018) Dopaminergic modulation of hemodynamic signal variability and the functional connectome during cognitive performance. Neuroimage. In press.
— Thanks also and in particular to our colleagues Christiane Thiel of Oldenburg, and Bernhard Sehm and Lorenz Deserno of Leipzig, who helped us made this large-scale L‑DOPA project happen!